TABLE 1.

Nucleotide substitutions between the genomes of the clones and fullGNM

Geneb	Nucleotide positiona	Nucleotide differencec			Deduced amino acid differenced
		cZ	cC	cCdi
Leader (1–55)	33		G→A	G→A
	34		T→C	T→C
	45		T→G	T→G
N (56–1,737), N CDS (120–1,694)	335		G→A	G→A
	483		A→Ge		T122Ae
	576			G→Te	D153Ye
	598		T→C	T→C	I160T
	953		A→G	A→G
	1257		T→C	T→C
	1294		G→A	G→A	G392E
	1394		C→T	C→T
	1410		A→G	A→G	K431E
	1415		C→T	C→T
	1451		T→A	T→A	D444E
	1646		T→C	T→C
	1708		T→C
P (1,741–3,633), P CDS (1,844–3,550), C CDS (1,854–2,468)	1760		C→T	C→T
	1907		C→A	C→A	D18Ef
	1984		A→G	A→G	E44Gf
	2032		T→C	T→C	L60Pf
	2381		A→G	A→G	S180Gg
	2500		T→C	T→C
	2878		A→G	A→G
	3370		T→C	T→C
	3393		C→A	C→A	P517H
	3453		T→C	T→C	V537A
	3601		C→T	C→T
	3602		C→T	C→T
M (3,636–4,809), M CDS (3,669–4,715)	3717		A→G	A→G	T17A
	3749		G→A	G→A
	3768		C→T	C→T	H34Y
	3780		G→A	G→A	V38I
	4167		C→T	C→T	L167F
	4220	G→A
	4265		T→C	T→C
	4271		T→C	T→C
	4272		T→C	T→C
	4498		A→C	A→C	N277T
	4499	T→C
	4587		A→C	A→C	M307L
F (4,813–6,633), F CDS (4,866–6,563)	4886		A→G	A→G
	5061		T→C	T→C	F66L
	5144		A→G
	5200		C→T	C→T	A112V
	5204		C→A	C→A
	5267		A→G	A→G
	5512		A→G	A→G	E216G
	5647	C→A	C→A	C→A	S261Y
	5663		A→T	A→T
	5714		C→T	C→T
	5756		T→A	T→A
	5777		A→G	A→G
	6332		G→T	G→T
	6420		A→G	A→G	I519V
	6442		G→A	G→A	R526K
	6494		C→T	C→T
	6545		A→G	A→G
	6600		A→G	A→G
HN (6,637–8,524), HN CDS (6,693–8,420)	6676		T→C	T→C
	6734		T→C	T→C
	6752		C→T	C→T
	6759		C→T	C→T	P23L
	6760		C→T	C→T	P23L
	6790		C→T	C→T	A33V
	6791		C→T	C→T	A33V
	6980		A→C	A→C
	7102		A→T	A→T	H137L
	7117			T→Ae	I142Ne
	7136		T→G	T→G	D148E
	7209		G→A	G→A	E173K
	7553		T→C	T→C
	7678		C→Ae		A329Ee
	7691		A→T	A→T
	7715		A→G	A→G
	7730		G→A	G→A
	7756		A→G	A→G	Q355R
	7771		T→C	T→C	V360A
	7834		G→A	G→A	S381N
	8095		A→C	A→C	K468T
L (8,528–15,327), L CDS (8,555–15,242)	8747		C→T	C→T
	8753		A→G	A→G
	9018		G→A	G→A	G155S
	9128		G→A	G→A
	9140	T→C	T→C	T→C
	9287		A→G	A→G
	9328		A→G	A→G
	9533		T→C	T→C
	9595		A→T	A→T	H347L
	9787			G→Te
	10049		A→G	A→G
	10158		G→A	G→A	E535K
	10292		A→G	A→G
	10295		C→T	C→T
	10298	G→C	G→C	G→C	R581S
	10316	G→A	G→A	G→A
	10428		G→A	G→A	E625K
	10433		T→G	T→G
	10475		A→G	A→G
	10952		G→A	G→A	I800T
	10954		T→C	T→C
	10969		G→A	G→A	G805D
	11110		A→G	A→G	K852R
	11525		T→C	T→C
	11661		G→Ae		E1036Ke
	11672		A→C	A→C
	12024		C→T	C→T
	12061		T→C	T→C
	12174		T→A	T→A	C1207S
	12821		C→T	C→T
	12872		T→C	T→C
	12923		C→T	C→T
	13031		T→C	T→C
	13137		T→C	T←C
	13163		T→C	T→C
	13298		T→C	T→C
	13769		T→C	T→C
	13850		T→C	T→C
	14348		C→T	C→T
	14486		C→T	C→T
	14707		C→T	C→T	P2051L
	15032		A→G	A→G
	15122		A→G	A→G
	15212		A→G	A→G
	15303		G→A	G→A
Trailer (15,328–15,384)	15353		A→T	A→T

^aNucleotide position on the 15,384- nt-long full-length SeV genome.

^bGenes and the leader and trailer regions are shown, with their nucleotide positions. Coding DNA sequences (CDS) and their nucleotide positions are also shown.

^cNucleotide difference compared with fullGNM of Z-cDNA.

^dAmino acid difference deduced from the nucleotide sequences.

^eNucleotide and amino acid substitutions found only between cC and cCdi.

^fAmino acid substitution found only in C, but not in P and V.

^gAmino acid substitution found in both P and V, but not in C.