. 2018 Feb 12;92(5):e01749-17. doi: 10.1128/JVI.01749-17

TABLE 4.

Differences in clinical outcomes between the presence and absence of HLA-A*29:01-, -B*07:05-, and -C*15:05-associated HIV-1 mutations

Gene product	Position	HLA-associated amino acid mutation	No. of patients with mutation	Median viral load (log₁₀ copies/ml)		P value^a	Median CD4 count (cells/μl)		P value^a
Gene product	Position	HLA-associated amino acid mutation	No. of patients with mutation	With mutation	Without mutation	P value^a	With mutation	Without mutation	P value^a
Pol	14	R	44	4.3	4.6	0.28	302	331	0.69
	110	K	123	4.6	4.5	0.19	325	326	0.60
	261	Y	26	4.2	4.5	0.31	313	326	0.69
	272	Non-I	133	4.6	4.5	0.61	293	341	0.051
	653	L	18	4.9	4.5	0.12	343	325	0.74
	653	A	36	4.6	4.5	0.43	200	335	0.0017
	653	T	24	4.7	4.5	0.29	196	333	0.0083
	655	V	46	4.7	4.5	0.17	270	331	0.35
	657	R	51	4.8	4.5	0.11	213	337	0.0026
Nef	71	K	53	4.7	4.5	0.091	272	335	0.075
	156	Non-N	276	4.5	4.7	0.059	337	304	0.30
	173	I	38	4.9	4.5	0.019	300	333	0.99

Analyzed by using the Mann-Whitney test. Values in bold indicate statistical significance (P < 0.05).