TABLE 1.
Characteristics of the subjects
| Parametera | Value for groupb |
Pc | |
|---|---|---|---|
| TC (n = 14) | PC (n = 17) | ||
| Age (yr), median (IQR) | 41 (38–52) | 45 (41–48) | 0.279 |
| Male sex, no. (%) | 8 (57) | 10 (59) | 0.925 |
| Sexual transmission, no. (%) | 10 (71) | 6 (35) | 0.049 |
| Time since diagnosis (yr), median (IQR) | 8 (2–14) | 18 (11–22) | 0.002 |
| HCV RNA detected, no. (%) | 6 (43) | 10 (59) | 0.376 |
| CD4+ T cells (cells/μl), median (IQR) | 625 (392–783) | 714 (627–940) | 0.208 |
| CD8+ T cells (cells/μl), median (IQR) | 735 (548–1015) | 648 (569–970) | 0.999 |
| CD4/CD8 ratio, median (IQR) | 1 (0.58–1.28) | 1.17 (0.67–1.55) | 0.456 |
| HLA B57, no. (%)d | 3 (21) | 6 (40) | 0.280 |
| HLA B27, no. (%)d | 1 (7) | 2 (13) | 0.584 |
| HLA B35, no. (%)d | 2 (14) | 0 (0) | 0.129 |
| IL28B-CC, no. (%)e | 3 (38) | 5 (42) | 0.728 |
a
IQR, interquartile range.
b
Values from transient controllers (TC) are taken from −T2, and values from persistent controllers (PC) are taken from the first time point of follow-up.
c
The Mann-Whitney U and chi-square tests were used. All P values of <0.05 were considered significant and are highlighted in bold.
d
n = 15 for PC.
e
n = 8 and n = 12 for TC and PC, respectively.