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. 2017 Jul 12;43(4):718–727. doi: 10.1038/npp.2017.101

Figure 3.

Figure 3

Excitability of GFP+ and GFP− striatal MSNs following cocaine memory retrieval. (a) In the nucleus accumbens shell (NAcshell), the spike counts of Paired CL mice were not significantly different between GFP+ neurons (n=5) and GFP− neurons (n=8); this was similar to the Unpaired CL group (GFP+ n=7; GFP− n=8). Right: example traces of Paired CL and Unpaired CL GFP+ and GFP− neurons at 150 pA stimulation from the NAcshell following cocaine memory retrieval. (b) In the nucleus accumbens core (NAccore), GFP+ neurons were significantly more excitable than GFP− neurons in Paired CL mice (GFP+ n=9; GFP− n=9) but not Unpaired CL mice (GFP+ n=7; GFP− n=7). Right: example traces of Paired CL and Unpaired CL GFP+ and GFP− neurons at 150 pA stimulation from the NAccore following cocaine memory retrieval. (c) Excitability of GFP+ and GFP− MSNs in the dorsal striatum (DS) (GFP+ Paired CL n=7, Unpaired CL n=8), (GFP− Paired CL n=6, Unpaired CL n=8). Right: example traces of Paired CL and Unpaired CL GFP+ and GFP− neurons at 180 pA stimulation from the DS following cocaine memory retrieval. All data are expressed as mean±SEM; n=number of animals. Scale bars, 20 mV, 200 ms.