Toluene-induced alterations to the intrinsic excitability of mPFC-NAc neurons of adolescent rats is transient. Figures show the effect of toluene exposure on firing of prelimbic and infralimbic mPFC neurons projecting to the core (a—Air: n=6, Toluene: n=6; c—Air: n=6, Toluene: n=6; e—Air: n=6, Toluene: n=6; g—Air: n=6, Toluene: n=6) or shell (b—Air: n=6, Toluene: n=6; d—Air: n=6, Toluene: n=6; f—Air: n=6, Toluene: n=6; h—Air: n=6, Toluene: n=6) of the NAc. Traces in each figure show examples of firing (evoked with a 250 pA current step) from air (left trace) or toluene (right trace) exposed rats 7 day following exposure to 10 500 p.p.m. toluene vapor. Data are presented as mean and SEM.