Table 1. Reinforcing Effectiveness of Bath Salts Constituents MDPV, Methylone, and Caffeine Alone and in Binary Mixtures.
MDPV : caffeine |
Methylone : caffeine |
MDPV : methylone |
||||
---|---|---|---|---|---|---|
Emax (±SEM) | Final ratio (±SEM) | Emax (±SEM) | Final ratio (±SEM) | Emax (±SEM) | Final ratio (±SEM) | |
Constituent 1 | 26.4 (1.0) | 1168 (168) | 14.8 (0.8) | 118 (18) | 26.3 (1.0) | 1207 (177) |
Constituent 2 | 8.7 (0.4) | 27 (3) | 8.3 (0.5) | 24 (3) | 18.1 (0.9) | 271 (70) |
10 : 1 Mixture | 25.5 (0.8) | 947 (156) | 16.2 (0.7) | 138 (20) | 24.1 (1.5) | 1007 (350) |
3 : 1 Mixture | 24.0 (0.7) | 672 (76) | 17.7 (1.0) | 208 (38) | 19.1 (0.6) | 246 (34) |
1 : 1 Mixture | 21.6 (0.9) | 445 (75) | 16.6 (0.8) | 157 (26) | 18.6 (1.1) | 266 (64) |
1 : 3 Mixture | 19.3 (0.6) | 256 (30) | 12.8 (0.4) | 62 (6) | 16.7 (0.9) | 169 (36) |