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. 2018 Feb 13;19:137. doi: 10.1186/s12864-018-4527-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Cell type specific predictors do show prognostic potential in patients of respective subtype. Predictors whose expression restricted to ER+, HER2+, and TNBC types were considered separately. They were analyzed separately using a multivariate Cox proportional hazard regression model only on the TCGA patients belonging to the subtype representing the cell type of interest. Analysis show that ER+ cell type specific predictors show better prognostic potential in TCGA ER+ patients compared to HER2+ and TNBC patients. Similarly, HER2+ and TNBC cell type specific predictors serve as better prognostic markers in HER2+ and TNBC patients respectively. P-values along with hazard ratios and confidence intervals are indicated