Table 2.
List of differentially abundant proteins with fold changes > 2 in liver of pre-harvest Atlantic salmon held at 15 °C and 21 °C
| # | Protein name (Entry name) | Fold change 21 °C vs. 15 °C |
Unique peptides | adj. p-value1 | Gene name | Human orthologue |
|---|---|---|---|---|---|---|
| 1 | Acyl-coenzyme A oxidase (C0H935) | −5.43 | 14 | < 0.001 | ACOX3 | ACOX3 |
| 2 | Leukocyte cell-derived chemotaxin 2 (B5XCD7) | −3.44 | 6 | 0.050 | LECT2 | LECT2 |
| 3 | Betaine-homocysteine methyltransferase (B5DGE7) | −3.43 | 13 | < 0.001 | bhmt | BHMT |
| 4 | 5′-nucleotidase (EC 3.1.3.5) (B5DGD0) | −3.29 | 3 | 0.009 | 5NT3L | NT5C3A |
| 5 | Uricase (EC 1.7.3.3) (Fragment) (Q3S563) | −3.26 | 16 | < 0.001 | ||
| 6 | Cytochrome P450 2 M1 (B5X2R4) | −3.16 | 7 | 0.014 | CP2M1 | |
| 7 | Tubulin folding cofactor B (B5X4J7) | −2.95 | 9 | < 0.001 | TBCB | TBCB |
| 8 | Elongation factor 2 (C0H9N2) | −2.87 | 9 | < 0.001 | EF2 | EEF2 |
| 9 | Sulfotransferase (EC 2.8.2.-) (B5X695) | −2.87 | 10 | 0.016 | ST2S2 | ST2S2 |
| 10 | Pyruvate kinase (EC 2.7.1.40) (C0HBL8) | −2.76 | 28 | < 0.001 | KPYK | KPYK |
| 11 | High mobility group protein B3 (C0HBT7) | −2.66 | 3 | < 0.001 | HMGB3 | HMGB3 |
| 12 | Costars family protein ABRACL (ABRA C-terminal-like protein) (ABRAL) | −2.63 | 3 | < 0.001 | ||
| 13 | Apolipoprotein A-I (B5XBH3) | −2.63 | 15 | < 0.001 | APOA1 | APOA1 |
| 14 | Heat shock cognate 70 kDa protein (B5DFX7) | −2.50 | 9 | < 0.001 | HSP70 | HSPA8 |
| 15 | Stathmin (B5X953) | −2.41 | 3 | 0.001 | STMN1 | STMN1 |
| 16 | Proliferating cell nuclear antigen (B9EMQ6) | −2.34 | 6 | < 0.001 | PCNA | PCNA |
| 17 | Translationally-controlled tumor like protein (B5XAC1) | −2.34 | 7 | < 0.001 | TCTP | TPT1 |
| 18 | Guanidinoacetate N-methyltransferase (B5DGB5) | −2.33 | 5 | < 0.001 | GAMT | GAMT |
| 19 | Lipase (B5X16) | −2.30 | 7 | 0.002 | LICH | LIPA |
| 20 | NDRG1 (B5X292) | −2.24 | 3 | 0.008 | NDRG1 | NDRG1 |
| 21 | Proactivator polypeptide (B5X4D6) | −2.20 | 7 | < 0.001 | SAP | PSAP |
| 22 | Peroxisomal trans-2-enoyl-CoA reductase (B5XAK8) | −2.16 | 7 | < 0.001 | PECR | PECR |
| 23 | Elongation factor-1 delta-1 (B5DGP8) | −2.13 | 5 | < 0.001 | ||
| 24 | Lupus La protein homolog B (C0HAU7) | −2.09 | 8 | < 0.001 | LAB | |
| 25 | Adenosine kinase a (B5DGF0) | −2.08 | 18 | < 0.001 | ||
| 26 | Plasminogen activator inhibitor 1 RNA-binding protein (B5X326) | −2.03 | 4 | < 0.001 | PAIRB | SERBP1 |
| 27 | Beta-carotene oxygenase 2 like (K8DW80) | −2.02 | 6 | < 0.001 | bco2 | BCO2 |
| 28 | Apolipoprotein B (Fragment) (Q91480) | 2.05 | 8 | 0.016 | APOB | |
| 29 | UDP-glucuronosyltransferase (EC 2.4.1.17) (B5X180) | 2.16 | 4 | 0.014 | UD2A2 | UGT2A1 |
| 30 | 15-hydroxyprostaglandin dehydrogenase (B9EPG3) | 2.19 | 11 | < 0.001 | PGDH | HPGD |
| 31 | Phenazine biosynthesis-like domain-containing protein 2 (C0H855) | 2.33 | 11 | < 0.001 | PBLD2 | PBLD |
| 32 | Metallothionein B (MT-B) (MTB) | 2.33 | 2 | 0.004 | mtb | |
| 33 | Serpin H1 (B5X1Q5) | 3.07 | 4 | 0.004 | SERPH | SERPINH1 |
| 34 | Ferritin (C0H793) | 3.16 | 8 | < 0.001 | FRIM | FTL |
| 35 | Digestive cysteine proteinase 2 (B5X4D9) | 3.63 | 7 | < 0.001 | CYSP2 | |
| 36 | Canopy homolog 2 (B5XA82) | 4.41 | 5 | < 0.001 | CNPY2 | CNPY2 |
| 37 | Erythrocyte band 7 integral membrane protein (B5X1V0) | 5.01 | 6 | 0.005 | STOM | STOM |
Reported proteins with p-values < 0.05 after adjustment for multiple testing using the Benjamini Hochberg correction