Table 4.

Multivariate Cox regression analysis of the covariates affecting OS

	HR	95% CI	p
ΔSMI%* during neoadj. (>median vs. <median)	-0.609	0.297–0.997	0.049
N stage (per level)	0.486	0.940–2.801	0.082
T stage (per level)	0.496	0.993–2.892	0.086
CCI** (per level)	0.175	0.973–1.459	0.091

^*The percentual change in skeletal muscle index during neoadjuvant treatments

^**Charlson comorbidity index