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. 2018 Feb 12;18:174. doi: 10.1186/s12885-018-4021-6

Table 1.

Clinical information cohort 1

Patient ID Sample PAM50 subtype ER PR HER2 HER2 CNV (exome data) AdjCT AdjHT AdjRT DFI Relapse site Relapse to death
P1 Primary Tumor
Metastasis
3 NA
Luminal B
+
-
+
-
-
-
HER2-
HER2-
+ + + 3.3 liver 3.2
P2 Primary Tumor
Metastasis
3 NA
Basal like
-
NA
-
NA
-
NA
HER2-
HER2-
+ + 1.4 lymph 4.9
P3 Primary Tumor
Metastasis
3 Na
Luminal B
-
-
+
-
-
NA
HER2-
HER2-
+ 4.1 liver 1.5
P4 Primary Tumor
Metastasis
3 NA
Basal like
-
NA
-
NA
NA
NA
HER2+ (CN 3.5)
HER2+ (CN 3.5)
+ + + 8.1 lung 6.0
P5 Primary Tumor
Metastasis
N/A NA
Luminal A
+
+
-
-
-
NA
HER2-
HER2+ (CN 2.5)
+ + 3.5 liver 5.7
P6 Primary Tumor
Metastasis
3 NA
HER2 enriched
+
+
+
-
NA
-
HER2-
HER2-
+ + + 2.6 lymph 1.1
P7 Primary Tumor
Metastasis
2 NA
Normal like
+
+
+
-
NA
-
HER2-
HER2-
+ + + 4.8 skin 0.8
P8 Primary Tumor
Metastasis
NA
NA
+
+
+
+
-
-
HER2+ (CN 2.4)
HER2- (CN 0.8)
+ + + 5 a liver 0.7
P9 Primary Tumor
Metastasis
NA
NA
-
-
-
-
NA
-
HER2-
HER2-
+ + 11 a breast NA
P10 Primary Tumor
Metastasis
NA
NA
+
+
+
+
-
-
HER2-
HER2-
+ + + 4 a bone 0.4

Receptor status by IHC (immunohistochemistry)

ER estrogen receptor, PR progesteron, HER2 Her2 receptor status, HER2 CNV amplification of Her2 derived from exome data, AdjCT adjuvant chemotherapy, AdjHT adjuvant hormone therapy, AdjRT adjuvant radiotherapy, DFI disease free interval (months); Relapse to death (months)

aapproximated as time from primary tumor surgery date to relapse diagnosis date