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. 2018 Feb 13;16:13. doi: 10.1186/s12951-018-0340-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Internalization of LDL peptide decorated PLA-coated MSNPs by RBECs. a TEM image of MSNPs (indicated by blue square) internalized by a RBEC. b TEM image of LDL peptide decorated PMSNPs (indicated by blue square) internalized by a RBEC, scale bar = 2 μm. The inset is an enlarged TEM image verifying the circular structures in side the cell are indeed mesoporous MSNPs. Scale bar = 100 nm. c Fluorescent images showing RBECs (cell membranes were stained with DiI, red fluorescence) cultured with LPMSNPs (green fluorescence). Many green LPMSNPs are seen inside of the RBEC cells. Scale bar = 10 μm