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. 2018 Feb 13;16:13. doi: 10.1186/s12951-018-0340-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — The effect of RSV released from LPMSNPs on PMA activated microglia. a The expression of NADPH p47^phox and Iba-1 by immunofluorescence assay. PMA activates NADPH p47^phox and up-regulates Iba-1 in HAPI microglia cells and increase superoxide production, which could be reduced by RSV. b The quantitive analysis of mean fluorescence intensity. *p < 0.05 vs control; ^#p < 0.05 vs only PMA stimulation