Table 3.
18F-FPEB binding potential throughout the brain as revealed by positron emission tomography (PET)
| Region | Control | Autism | t-value | P |
|---|---|---|---|---|
| Amygdala | 3.93 ± 0.64 | 3.69 ± 0.57 | 0.58 | 0.58 |
| Caudate nucleus | 4.28 ± 0.47 | 4.56 ± 0.62 | 0.67 | 0.52 |
| Cerebellum | 1.07 ± 0.10 | 1.25 ± 0.068 | 3.17 | 0.016 |
| Cingulate | 4.33 ± 0.43 | 4.42 ± 0.23 | 0.42 | 0.68 |
| Entorhinal area | 1.78 ± 0.71 | 2.75 ± 0.59 | 2.19 | 0.065 |
| Frontal lobe | 4.11 ± 0.39 | 4.28 ± 0.22 | 0.87 | 0.41 |
| Fusiform gyrus | 3.86 ± 0.49 | 3.69 ± 0.52 | 0.47 | 0.65 |
| Globus pallidus | 1.12 ± 0.14 | 1.28 ± 0.15 | 1.58 | 0.16 |
| Hippocampus | 3.74 ± 0.67 | 3.66 ± 0.52 | 0.21 | 0.84 |
| Insula | 4.58 ± 0.62 | 4.49 ± 0.51 | 0.22 | 0.83 |
| Occipital lobe | 3.22 ± 0.39 | 3.35 ± 0.15 | 0.79 | 0.46 |
| Paracentral gyrus | 2.89 ± 0.44 | 3.36 ± 0.32 | 1.83 | 0.11 |
| Parahippocampus | 3.25 ± 0.09 | 3.55 ± 0.40 | 1.22 | 0.26 |
| Parietal lobe | 3.93 ± 0.36 | 4.10 ± 0.14 | 1.08 | 0.32 |
| Precentral gyrus | 3.55 ± 0.38 | 3.86 ± 0.12 | 1.89 | 0.10 |
| Precuneus | 3.87 ± 0.24 | 4.19 ± 0.20 | 2.13 | 0.071 |
| Postcentral gyrus | 3.44 ± 0.22 | 3.82 ± 0.20 | 2.60 | 0.036 |
| Putamen | 3.90 ± 0.54 | 4.18 ± 0.33 | 0.91 | 0.39 |
| Temporal lobe | 4.23 ± 0.57 | 4.23 ± 0.30 | 0.02 | 1.00 |
| Thalamus | 2.43 ± 0.28 | 2.50 ± 0.29 | 0.37 | 0.72 |
| Ventral striatum | 4.75 ± 0.66 | 5.10 ± 0.50 | 0.89 | 0.40 |
Italicized values represent significant or near-significant findings