Fig. 3.

Effects of P.gingivalis-LPS on spatial learning of mice during the Morris water maze (MWM) test. Effects of treatment with P.gingivalis-LPS (5 mg kg⁻¹, i.p.) alone or in combination with TAK-242 (5 mg kg⁻¹, i.p.) on latency to find the platform during the acquisition phase of the MWM test. Data are presented as mean ± SEM; *p < 0.05, **p < 0.01 and ***p < 0.001, compared to the control group; ^#p < 0.05 and ^##p < 0.01, compared to the P.gingivalis-LPS group