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Hypothetic scheme illustrating multiple regulatory pathways of the anti-aging effects of let-7g in human umbilical vein endothelial cells. SIRT1, sirtuin 1; LOX-1, lectin-like ox-LDL receptor-1; ox-LDL, oxidized low-density lipoprotein; IGF1R, insulin-like growth factor 1 receptor; TP53, tumor protein 53.
