Table 3.
Oxidative stress parameters, non-enzyme and enzyme antioxidant defense systems in the sentinel lymph node (SLN) of women with breast cancer.
| Negative SLN | SLN with micrometastases | SLN with macrometastases | |
|---|---|---|---|
| Oxidative stress parameters | |||
| Total antioxidant capacity (nmol of Trolox equivalents/mg of protein) | 8.86 ± 0.09 | 9.88 ± 0.1 | 11.57 ± 0.1 |
| Lipid peroxidation (ng of malondialdehyde/mg of protein) | 564.8 ± 7.1 | 629.4 ± 10.2 | 497.5 ± 11.9 |
| Protein oxidation (nmol per mg of protein) | 53.0 ± 0.9 | 53.1 ± 1.06 | 48.9 ± 1.02 |
| Non-enzymatic antioxidant defenses | |||
| GSH (ng per mg of protein) | 9.4 ± 0.1 | 9.38 ± 0.1 | 8.9 ± 1.1 |
| Enzymatic antioxidant defenses | |||
| Superoxide dismutase (percentage of inhibition) | 58.9 ± 0.3 | 71.5 ± 0.6 | 72.6 ± 0.4 |
| Catalase (nmol/min/mg of protein) | 56.8 ± 0.2 | 72.7 ± 0.4 | 74.1 ± 0.5 |
| Glutathione peroxidase (µmol/min/mg of protein) | 1.63 ± 0.01 | 1.63 ± 0.01 | 1.45 ± 0.009 |