Table 2.
Baseline characteristics of participants in the GBR study as genotyped by their carrier status of PPARG Pro12Alaa.
| GBR study |
||||
|---|---|---|---|---|
| Phenotype | Pro/Pro (n = 12) | Pro/Ala (n = 15) | Ala/Ala (n = 13) | p value |
| Age | 64 (9) | 63 (9) | 64 (8) | 0.92 |
| Women (%) | 8 (67) | 9 (60) | 9 (69) | 0.92 |
| BMI (kg/m2) | 26.8 (3.3) | 24.3 (3.2) | 26.6 (3.6) | 0.71 |
| Waist–hip ratio | 0.91 (0.06) | 0.89 (0.08) | 0.92 (0.07) | 0.85 |
| Fat percentage (%) | 32.3 (8.8) | 30.5 (6.6) | 32.9 (7.1) | 0.66 |
| Fasting glucose (mmol/L) | 5.88 (0.48) | 5.83 (0.52) | 5.89 (0.52) | 0.57 |
| Total cholesterol (mmol/L) | 5.41 (0.60) | 5.63 (0.80) | 6.05 (0.90) | 0.13 |
| HDL cholesterol (mmol/L) | 1.51 (0.34) | 1.49 (0.31) | 1.59 (0.27) | 0.42 |
| LDL cholesterol (mmol/L) | 3.40 (0.54) | 3.48 (0.65) | 3.85 (0.93) | 0.23 |
| Triglycerides (mmol/L) | 0.86 (0.27) | 1.07 (0.48) | 1.20 (0.48) | 0.12 |
aThe numbers given are either counts, percentages, or mean (standard deviation). The reported p values of the association between the phenotype and copies of the minor allele come from linear regressions adjusted for age, sex, and ancestry components under an additive model. The p value for age and sex comes from an ANOVA and a Fisher’s exact test, respectively. The beta from the regression is not shown. Use of medication is self-reported.
HDL: high-density lipoprotein; LDL: low-density lipoprotein. There was a varying number of missing observations for different phenotypes.