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. 2018 Jan 17;41(4):2086–2098. doi: 10.3892/ijmm.2018.3393

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Copyright: © Yuan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Changes to the p-4EBP1 protein expression levels in the auditory cortex with aging in the NS and D-gal-induced mimetic aging rats. The effects of D-gal treatment on the expression of p-4EBP1 in the (A) 3-, (B) 9- and (C) 15-month-old NS and D-gal groups as determined by western blotting. There was no obvious correlation between p-4EBP1 and autophagy-related proteins. β-actin was used as a loading control. Data are expressed as mean + standard error of the mean. ^*P<0.05 and ^**P<0.01 vs. the age-matched NS subgroups. NS, normal saline; D-gal, D-galactose; p, phosphorylated; Atg, autophagy-related protein.