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. 2018 Jan 30;41(4):2139–2149. doi: 10.3892/ijmm.2018.3439

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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miR-139-5p inhibits the Wnt/β-catenin pathway via targeting Fms-related tyrosine kinase 1 (Flt1) in glioma cells. (A) Western blot assays were performed to measure the impact of Flt1 on the levels of Wnt1, GSK-3β, p-GSK-3β and β-catenin in U87 cells. (B) Western blot assays were performed to examine the influence of miR-139-5p on the levels of Wnt1, GSK-3β, p-GSK-3β and β-catenin in U87 cells. (C) Western blot assays were performed to determine the restoration of Flt1 reverse effect of miR-139-5p on the levels of Wnt1, GSK-3β, p-GSK-3β and β-catenin in U87 cells.