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. 2018 Feb 5;9:157. doi: 10.3389/fimmu.2018.00157

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Copyright © 2018 Agrawal, Parkash, Palaniappan, Bhatia, Kumar, Chauhan and Madhan Kumar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of various markers and cellular subsets in PBMCs of QFT –ve (NHS), QFT +ve (NHS), and PTB. (A) Mean fluorescent intensity (MFI) of (i) CD25, (ii) CD4, (iii) CD39 markers in lymphocytes, and (iv) percentage of CD25 T cells in lymphocytes. (B) Frequencies of (i) CD4⁺CD25⁺, (ii) CD4⁺CD39⁺ T cells, (iii) CD4⁺CD25⁺FoxP3, and (iv) CD4⁺CD25⁺CD39⁺ Treg. Statistical analysis was performed using Mann–Whitney U test *p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001. PBMCs, peripheral blood mononuclear cells; QFT, quantiferon; PTB, pulmonary TB patients; ns, not significant.