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. 2018 Jan 31;9:52. doi: 10.3389/fphys.2018.00052

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Copyright © 2018 Zhu, Guo, Ban, Song, Liu, Pelosi and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Amino acid sequences of NPC2 proteins of Lepidoptera. (A) Phylogenetic tree constructed with the NPC2 protein sequences of some representative Lepidopteran species. Accession numbers are preceded by species abbreviations as follows. Atra: Amyelois transitella; Bmor: Bombyx mori; Dple: Danaus plexippus; Harm: Helicoverpa armigera; Pxut: Papilio xuthus; Pxyl: Plutella xylostella. (B) Alignment of the nine amino acid sequences encoded by NPC2 genes in the genome of H. armigera. (C) Alignment of representative orthologues of HarmNPC2-1, the protein investigated in the present work and indicated by an arrow.