Figure 4. Comparison of the positions of Cα atoms between A2AAR–UK432097, D52N–UK432097, and A2AAR–ZM241385.
All three structures were aligned globally and the root-mean-square deviation (RMSD) was calculated between Cα atoms of the same residue number between (a) A2AAR–UK432097 and D52N–UK432097 and (b) A2AAR–UK432097 and A2AAR–ZM241385, and (c) D52N–UK432097 and A2AAR–ZM241385. Residue number is plotted on the horizontal axis and RMSD is plotted on the vertical axis. The observed RMSDs are colored according to the legends in the figure panels. Roman numerals indicate helix numbers, blue shading indicates positions of intracellular loops, and red shading indicates positions of extracellular loops.