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. Author manuscript; available in PMC: 2019 Feb 15.
Published in final edited form as: Life Sci. 2017 Dec 27;195:1–5. doi: 10.1016/j.lfs.2017.12.030

Figure 1.

Figure 1

Effect of CB1/CB2 double knockout on infarct volume, infarct fraction, and clinical score in a mouse model of permanent ischemia (photoinjury). A: X axis: genotype, Y axis, infarct volume in mm3. Double knockout (DKO) mice show significantly smaller infarct volume as compared to wild type controls (p = 0.0002). B: X axis: genotype, Y axis, infarct fraction as a percent of the whole ipsilateral hemisphere. DKO mice show significantly smaller infarct fraction as compared to wild type controls (p = 0.0014). C: X axis: genotype, Y axis, outcome of the neurological assessment (a higher score indicates more severe impairment). DKO mice show significantly improved neurological performance compared to wild type controls (p = 0.003).