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Engineered cells expressing nerve growth factor can help reverse Alzheimer’s disease in patients. Averaged FDG PET scans in four subjects treated with NGF, overlaid on standardized MRI templates. Representative axial sections, with 6–8 months between the first and second scan, showing widespread increases in brain metabolism. Flame scale indicates FDG use/100 g tissue/min; red color indicates more FDG use than blue color. Reproduced with permission.[127] Copyright 2005, Nature.
