Table 1.

Comparison among first (2006), second (2012), and third (2017) revisions of the Korean Medication Algorithm for Depressive Disorder

	First revision in 2006	Second revision in 2012	Third revision in 2017
Depressive episode	Mild	Mild to moderate	Same as 2012
	Moderate	Non-psychotic severe
	Non-psychotic severe	Psychotic severe
	Psychotic severe
AD dosage and duration of treatment	Present	Deletion	Change: duration of initial treatment and number of choosing AD as initial treatment
Subtype	Dysthymia	Dysthymia	Dysthymia
	Minor depressive disorder	Minor depressive disorder	Minor depressive disorder
	Atypical features	Atypical features	Atypical features
	Melancholic features	Melancholic features	Melancholic features
		Seasonal pattern	Seasonal pattern
			Mixed features
			Anxious distress
Comorbid physical illness	Absent	Newly added	Same as 2012
Special population	Child only	Child and adolescent	Same as 2012
		Elderly
		Women
Non-pharmacological biological therapy	ECT only	Including TMS, phototherapy, nutritional therapy, sleep deprivation, VNS, DBS as well as ECT	Same as 2012
Response rate of review committee	66.3% (67/101)	54.5% (67/123)	54.9% (79/144)

AD, antidepressant; ECT, electroconvulsive therapy; TMS, transcranial magnetic stimulation; VNS, vagal nerve stimulation; DBS, deep brain stimulation.