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. 2017 May 26;8(8):1618–1630. doi: 10.1080/21505594.2017.1325975

Figure 1.

Figure 1.

Midgut and fat body-specific changes in DNA methylation in uninfected Bt-resistant G. mellonella larvae. (A) Global DNA methylation level in the midgut and fat body of uninfected Bt-resistant G. mellonella larvae (resistant line) and uninfected susceptible larvae (susceptible line) (*** p < 0.0005 - compared with susceptible line for the same organ). (B) Transcriptional activation of the DNA methyltransferase 1-associated protein 1 and DNA cytosine-5 methyltransferase genes in the fat body and midgut of uninfected Bt-resistant G. mellonella larvae relative to expression in the fat body and midgut of uninfected susceptible larvae (** p < 0.005 – compared with fold expression in the midgut and fat body of susceptible line). The 18S rRNA housekeeping gene was used for internal data normalization. Data are means of 3 independent experiments with standard deviations.