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. Author manuscript; available in PMC: 2019 Feb 8.
Published in final edited form as: Cell. 2018 Feb 8;172(4):683–695.e15. doi: 10.1016/j.cell.2018.01.005

Figure 7. Loss of FSIs impairs striatum-dependent egocentric learning.

Figure 7

(A,B) FSI-lesions do not impair accuracy on training trials in egocentric-allocentric operant task (N=8 mice per group; two-way ANOVA PGroup >0.9). (C,D) Probe trials initiated at different nosepokes reveal change in task strategy (N=8 mice per group; unpaired two-tailed t-test P<0.01). (E,F) FSI-lesioned mice perform equivalently at locating hidden platform in water T-maze (N=8 mice per group; two-way ANOVA PGroup>0.3). Arrows indicate sessions containing probe trials. (G,H) Probe trials initiated on opposite end of the maze reveal decreased utilization of egocentric strategy (N=8 mice per group; rank sum test P<0.002). All error bars are s.e.m. and center values are group means.