. 2014 Dec 28;18(6):3358–3373. doi: 10.1111/hex.12327

Table 4.

Descriptive statistics for quality of life scores at baseline, 6 and 12 weeks

	Baseline			6 Weeks			12 Weeks			P‐value
	n	Mean	SD	n	Mean	SD	n	Mean	SD	P‐value
Global health status
Total survivors	21	66.67	21.89	21	65.87	25.8	21	72.62	21.43	0.059
Group 1	9	60.19^a	26.28	9	50^a	229.17	9	58.33	23.94	0.374
Group 2	12	71.53^a	17.57	12	77.78	15.21	12	83.33^a	11.24	0.023
Physical functioning
Total survivors	21	88.89	10.61	21	86.98	15.27	21	86.67	17.51	0.778
Group 1	9	87.41^ab	9.69	9	77.04^aא	17.67	9	75.56^b≠	21.34	0.164
Group 2	12	90^ǂ	11.54	12	94.44^א	7.43	12	95^ǂ≠	7.03	0.050
Role functioning
Total survivors	21	74.6	28.68	21	74.6	31.01	21	77.78	22.57	0.827
Group 1	9	62.96	29.79	9	53.7^€	35.14	9	59.26^£	16.9	0.626
Group 2	12	83.33	25.62	12	90.28^€	15.01	12	91.67^£	15.08	0.531
Emotional functioning
Total survivors	21	79.31	21.81	21	71.11^aǂ	25.97	21	82.62^aǂ	13.73	0.031
Group 1	9	76.55^a	16.79	9	62.04^ab	31.21	9	76.85^b	13.68	0.241
Group 2	12	81.39	25.47	12	77.92	20	12	86.94	12.61	0.149
Cognitive functioning
Total survivors	21	79.37	18.93	21	76.19	23.9	21	79.37	20.35	0.617
Group 1	9	70.37^a	20.03	9	59.26^aß	25.15	9	66.67^ð	22.05	0.508
Group 2	12	86.11	15.62	12	88.89^ß	12.97	12	88.89^ð	12.97	0.751
Social functioning
Total survivors	21	70.64	23.51	21	74.6	29.16	21	76.98	28.61	0.602
Group 1	9	62.96	23.24	9	53.7^Þ	27.36	9	55.56^ø	27.64	0.802
Group 2	12	76.39^abǂ	22.98	12	90.28^aǂÞ	19.41	12	93.06^bø	16.6	0.037
Fatigue
Total survivors	21	32.27	20.46	21	30.68	21.35	21	33.32	24.35	0.282
Group 1	9	39.51^a	15.82	9	44.44^Ɣ	15.71	9	51.85^aƕ	22.22	0.237
Group 2	12	26.84	22.46	12	20.36^Ɣ	19.44	12	19.43^ƕ	15.07	0.222
Nausea and vomiting
Total survivors	21	6.35	11.15	21	7.14	9.96	21	3.97	7.27	0.386
Group 1	9	12.96^ƛ	13.89	9	12.96^Ʊ	11.11	9	7.4	8.78	0.571
Group 2	12	1.39^ƛ	4.81	12	2.78^Ʊ	6.49	12	1.39	4.81	0.647
Pain
Total survivors	21	21.43	24.23	21	18.25	16.59	21	15.08	18.18	0.272
Group 1	9	31.48	28.19	9	27.78^Ƹ	14.43	9	29.63^ϕ	18.22	0.927
Group 2	12	13.89	18.58	12	11.11^Ƹ	14.79	12	4.17^ϕ	7.54	0.353
Dyspnoea
Total survivors	21	12.7^a	19.65	21	22.22	32.2	21	25.4^a	25.61	0.131
Group 1	9	14.81^ab¥ɫ	17.57	9	44.44^a¥ϡ	33.33	9	44.44^bɫɄ	23.57	0.026
Group 2	12	11.11	21.71	12	5.56^ϡ	19.25	12	11.11^Ʉ	16.41	0.348
Insomnia
Total survivors	21	33.33	36.51	21	28.57	28.45	21	36.51	33.17	0.259
Group 1	9	48.15	44.44	9	40.74^a	32.39	9	55.56^aɅ	33.33	0.407
Group 2	12	22.22	25.95	12	19.44	22.29	12	22.22^Ʌ	25.94	0.606
Appetite loss
Total survivors	21	14.29	16.9	21	14.29	19.92	21	11.11	19.24	0.609
Group 1	9	22.22	16.67	9	18.52	24.22	9	18.52	24.22	0.853
Group 2	12	8.33	15.08	12	11.11	16.41	12	5.56	12.97	0.237
Constipation
Total survivors	21	17.46	20.05	21	12.7	24.67	21	15.87	29.1	0.650
Group 1	9	25.93	22.22	9	22.22	33.33	9	22.22	37.27	0.962
Group 2	12	11.11	16.41	12	5.56	12.97	12	11.11	21.71	0.402
Diarrhoea
Total survivors	21	6.35	13.41	21	9.52	18.69	21	7.94	17.97	0.736
Group 1	9	14.81^Ɏ	17.57	9	22.22^ʡ	23.57	9	18.52^ξ	24.22	0.764
Group 2	0	0^Ɏ	0	0	0^ʡ	0	0	0^ξ	0	–
Financial difficulties
Total survivors	21	28.57	33.81	21	25.4	36.37	21	25.4	34.81	0.629
Group 1	9	37.04	38.89	9	37.04	42.31	9	37.04	42.31	1.000
Group 2	12	22.22	29.59	12	16.67	30.15	12	16.67	26.6	0.402

Matched symbols (e.g. ǂǂ ) indicate statistically significant difference between pairs and matched letters (e.g. aa) indicate a clinically significance difference as defined as a 10‐point difference in functioning scores (Osaba et al 1998).