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. 2018 Jan 16;12(12):1092–1100. doi: 10.1080/15592294.2017.1403692

Figure 3.

Figure 3.

Effect size of association between urine cotinine levels and DNA methylation in monocytes. A volcano plot depicts the significance [-log10(P value), y-axis] vs. the effect size (beta, x-axis) from the associations between DNA methylation (M-value) and log urine cotinine levels (ng/ml) for each of the 484,817 CpG sites investigated (significant results not previously identified shown as golden circles; top seven most significant genomic loci shown as green circles; red line indicates genome-wide significance, FDR < 0.01).