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. Author manuscript; available in PMC: 2018 Jun 12.
Published in final edited form as: Nat Biomed Eng. 2017 Dec 12;1:977–982. doi: 10.1038/s41551-017-0168-8

Figure 2. Synthesis and characterization of PSMA-targeting dextran.

Figure 2

a) Synthetic scheme of PSMA targeting Dex10 urea-Dex10 (compound 3); b) PSMA receptor binding abilities of Dex10 (compound 1) and urea-Dex10 (compound 3) from a fluorescence-based assay for the inhibition on the hydrolysis of N-acetylaspartylglutamate (NAAG) to glutamate by the lysates of PSMA-positive human prostate adenocarcinoma (LNCaP) cells for 2 hours. Ki = 2 nM for urea-Dex 10.