Table 2. Fold changes in HuNoV and HuSaV RNA levels at 120 hpi relative to 0 hpi in cells (cell lysates) inoculated with HuNoV or HuSaV in medium supplemented with bacteria or the culture supernatants of co-culturing bacteria and immune cells.
| Cell name | Inoculated viruses and genotype | Bacteria culture sup | Culture Sup of co-culturing bacteria and immune cells | ||||||
|---|---|---|---|---|---|---|---|---|---|
| LGG | Nissle | LR | LA | LGG | Nissle | LR | LA | ||
| HIEC | NoV GII.4 mixa | 2.4 | 1.9 | 2.0 | 2.0 | 1.9 | 1.9 | 1.9 | 1.8 |
| SaV GI.2 | 1.5 | 1.5 | 1.3 | 1.8 | 1.5 | 1.3 | 1.7 | 1.4 | |
| HT29-Cl.16E | NoV GII.4 mixa | 1.7 | 2.0 | 2.1 | 2.2 | 1.9 | 1.8 | 1.7 | 1.2 |
| SaV GI.2 | 1.6 | 1.5 | 1.3 | 1.4 | 1.4 | 1.4 | 1.5 | 1.5 | |
| Caco-2 | NoV GII.4 mixa | 1.8 | 2.0 | 1.9 | 1.7 | 2.0 | 2.0 | 1.9 | 2.0 |
| SaV GI.2 | 2.1 | 1.5 | 1.4 | 1.7 | 1.7 | 1.7 | 1.9 | 2.0 | |
| IPEC-J2 | NoV GII.4 mixa | <0.1 | <0.1 | NT | NT | 1.2 | 1.2 | 2.3 | 2.1 |
| SaV GI.2 | 1.4 | 1.9 | 1.2 | 1.8 | 1.8 | 1.7 | 1.5 | 1.8 | |
| Vero | NoV GII.4 mixa | 2.0 | 2.1 | 2.4 | 2.0 | 2.1 | 1.9 | 2.0 | 1.4 |
| SaV GI.2 | 1.4 | 1.3 | 1.3 | 1.7 | 1.7 | 1.6 | 0.7 | 0.4 | |
NT: not tested.
a The mixture of HS66, HS194, HS292, and HS288.