Table 2. Percentage changes of vascular and metabolic parameters compared with the baseline at each time point and P values of comparisons between the treated and control groups.
| Control (n = 8) | Treated (n = 10) | P Value | |
|---|---|---|---|
| Ktrans (min-1) | |||
| 4 Hours | -6.04(-21.04, 8.97) | -39.91(-52.64, -27.18) | 0.018 |
| 1 Week | -29.90(-66.07, 6.27) | -27.35(-45.62, -9.08) | 0.822 |
| iAUC (mmol/sec) | |||
| 4 Hours | 6.23(-17.75,30.21) | -49.71(-65.47, -33.95) | 0.013 |
| 1 Week | -24.15(-53.84,5.55) | -18.87(-38.17, 0.43) | 0.797 |
| SUVmax | |||
| 4 Hours | -15.57(-52.41, 21.27) | -7.97(-25.83, 9.89) | 0.757 |
| 1 Week | 4.89(-23.17, 32.95) | -16.42(-35.03, 2.18) | 0.299 |
| SUVmean | |||
| 4 Hours | -14.82(-51.87, 22.23) | -10.05(-30.41, 10.30) | 0.852 |
| 1 Week | -0.76 (-27.03, 25.51) | -21.92(-42.63, -1.21) | 0.303 |
| MTV (cm3) | |||
| 4 Hours | 30.74(14.05, 47.72) | 37.82(16.61, 59.03) | 0.660 |
| 1 Week | 208.87(145.75, 272.00) | 118.34(76.59, 160.10) | 0.044 |
| TLG | |||
| 4 Hours | 195.96(129.96, 261.97) | 42.23(2.68, 81.77) | 0.623 |
| 1 Week | 209.64(108.00, 311.28) | 79.43(3.74, 155.14) | 0.101 |
Data are relative percentage changes determined by comparing the value at baseline with that at follow-up. Data in parentheses are 95% confidence intervals.
Ktrans: volume transfer coefficient
iAUC: initial area under the gadolinium concentration-time curve until 60 seconds
SUV: standardized uptake value
MTV: metabolic tumor volume
TLG: total lesion glycolysis