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. 2018 Feb 1;14(2):e1006858. doi: 10.1371/journal.ppat.1006858

Fig 5. Host transcriptome of Y. pseudotuberculosis-infected ceca.

Fig 5

(A) Principal component analysis (PCA) of mean centered and scaled rlog transformed read count values of tissue RNA-seq data of uninfected and Yersinia-infected mice. (B) Heat map of the top enriched host transcripts based on DESeq2 analyses. Color-coding is based on rlog transformed read count values. (C) Heat map illustrates log2 fold changes of host transcripts detected in YPIII- or YP147(ΔcnfY)-infected mice compared to uninfected mice (adjusted P value ≤ 0.05). Grey boxes: not significant. (D) Venn-diagram of differentially expressed genes from uninfected versus YPIII or YP147(ΔcnfY) 5 dpi.