Figure 8. Schematic Summary of Findings.
(A) NMS-expressing neurons are localized in the core, central, and shell regions of the SCN and encompass the majority of VIP- and AVP-expressing neurons but do not overlap with GRP-producing neurons. A small number of VIP- or AVP-expressing neurons (~5% each) that do not express NMS are not depicted here.
(B) Green cells represent Nms neurons. Lengthening the intracellular circadian period of Nms neurons lengthens behavioral circadian period. Abolishing molecular rhythmicity of Nms neurons or blocking synaptic transmission from Nms neurons leads to the loss of coherent circadian rhythms.