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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: DNA Repair (Amst). 2018 Jan 9;62:18–27. doi: 10.1016/j.dnarep.2018.01.004

Figure 7. OGG1-DNA crosslinks are repaired more efficiently when present on a template strand than when present on a coding strand.

Figure 7

Plasmid pLC119/pLC120 DNA substrates containing an OGG1 crosslink present on the template strand (left), or coding strand (right) of a transcriptional unit (construction described in Methods) were transfected into wild-type (V79, dark bars) and NER-deficient (V-H1, light bars) cells, and repair assays performed as described above. The graph depicts mean percent repair, ± SEM, N=3, *P < 0.05.