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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Card Fail. 2017 Oct 16;24(2):90–100. doi: 10.1016/j.cardfail.2017.10.010

Table 2.

PET and Echocardiographic Measurements by Diastolic Function

Characteristic Normal
(n = 34)		 Indeterminate
(n = 26)		 Abnormal
(n = 13)
Positron Emission Tomography
Total resting myocardial blood flow, mL/min/g 1.66 ± 0.55 1.62 ± 0.55 2.11 ± 0.48*
Total stress myocardial blood flow, mL/min/g 3.48 ± 0.90 2.86 ± 0.82 3.32 ± 0.88*
Myocardial flow reserve, stress/rest ratio 2.26 ± 0.81 1.91 ± 0.56 1.63 ± 0.49*
Echocardiography
Ejection fraction, % 62.5 ± 4.81 64.0 ± 3.75 65.4 ± 5.19
Left ventricular end-diastolic diameter, mm 46.0 ± 4.06 48.2 ± 5.91 45.8 ± 6.33
Left atrial end-systolic diameter, mm 37.7 ± 4.49 41.4 ± 5.41 43.7 ± 8.27*
Left atrial end-systolic volume index, ml/m2 25.0 ± 6.00 38.6 ± 10.9 42.5 ± 8.52*
Relative wall thickness 0.44 ± 0.10 0.44 ± 0.10 0.54 ± 0.09*
LV mass index, g/m2 82.3 ± 19.4 96.1 ± 26.0 107.0 ± 27.5*
E wave velocity, cm/s 75.9 ± 21.2 74.2 ± 23.7 107.1 ± 32.8*
A wave velocity, cm/s 73.2 ± 20.7 84.7 ± 27.5 84.8 ± 28.4*
Septal e′ velocity, cm/s 8.18 ± 2.70 6.76 ± 3.24 5.87 ± 1.35*
Lateral e′ velocity, cm/s 10.6 ± 3.17 8.13 ± 3.44 6.57 ± 1.86*
Average E/e′ 8.70 ± 2.55 10.9 ± 3.04 18.4 ± 7.39*
TR velocity > 2.8 m/s 0 8 (31%) 6 (46%)*
Global left ventricular longitudinal strain, % 17 ± 2 16 ± 4 15 ± 3
Global left atrial longitudinal strain, % 31 ± 7 25 ± 7 24 ± 4*

Continuous values expressed as mean ± one unit standard deviation.

Strain expressed as absolute value of percentage of longitudinal deformation. Abbreviations: LV: left ventricle; MFR: myocardial flow reserve; TR: tricuspid regurgitation.

*

p < 0.05 for analysis of variance across diastolic function grades.