TABLE I.

MiRNA Target Site SNPs in the 3′-UTR of the TAP2 Gene

			MFE (kcal/mol)
SNP	MAF	Putative miRNAs	Major Allele	Minor Allele	ΔMFE (kcal/mol)
rs241452 A>G	0.302	hsa-miR-1206	−18.4	−18.0	0.4
		hsa-miR-6516-3p	−14.4	−14.0	0.4
rs241454 T>C	0.301	hsa-miR-4533	−20.2	−21.8	−1.6
		hsa-miR-6797-5p	−26.1	−26.7	−0.6
rs241456 C>T	0.301	hsa-miR-2110	−18.8	−20.5	−1.7
		hsa-miR-3150a-3p	−26.6	−26.8	−0.2
		hsa-miR-4450	−25.8	−23.4	2.4
		hsa-miR-450a-2–3p	−16.4	−16.9	−0.5
		hsa-miR-6763-5p	−22.6	−25.1	−2.5
		hsa-miR-6810-5p	−21.4	−21.4	0.0
		hsa-miR-6857-5p	−19.5	−19.8	−0.3
		hsa-miR-92a-1–5p	−19.9	−19.9	0.0
		hsa-miR-1270	−21.7	−16.8	4.9
		hsa-miR-4531	−14.5	−12.5	2.0
		hsa-miR-4683	−18.1	−14.4	3.7
		hsa-miR-620	−19.2	−14.3	4.9
rs17034 G>A	0.298	hsa-miR-1271-3p	−23.2	−28.0	−4.8
		hsa-miR-4763-5p	−20.2	−24.3	−4.1
		hsa-miR-4772-3p	−18.7	−23.6	−4.9
		hsa-miR-550a-3–5p	−17.6	−24.1	−6.5
		hsa-miR-550a-5p	−20.7	−27.2	−6.5
		hsa-miR-6894-3p	−15.3	−21.6	−6.3
		hsa-miR-4327	−25.5	−25.2	0.3
		hsa-miR-636	−25.3	−25.0	0.3
rs241453 C>T	0.287	hsa-miR-1302	−17.6	−14.7	2.9
		hsa-miR-4298	−31.0	−28.1	2.9
		hsa-miR-3134	−18.6	−18.6	0.0
		hsa-miR-4534	−18.8	−22.0	−3.2
		hsa-miR-8082	−18.7	−22.8	−4.1
rs2857101 A>G	0.287	hsa-miR-126-5p	−11.6	−11.6	0.0
		hsa-miR-4795-3p	−12.2	−12.2	0.0
		hsa-miR-944	−12.7	−12.7	0.0
		hsa-miR-6731-3p	−10.9	−12.8	−1.9

Abbreviations: MAF, minor allele frequency; MFE, minimum free energy; ΔMFE, difference in MFE between wild-types and variants.