Table 4.
Demographics, Patient-Reported Outcomes, and Clinical Diagnosis as Predictors of Opioid Ordered or Higher Opioid Dosage (>120 MEQs/day) Ordered for MSKCC Pain Registry Patients (Encounter level analyses).
| Number of Encounters with specified outcome for that predictor used in the Regression Analysis: No/Yes (Number of Patients/analysis cell) | Opioid Ordered† | Number of Encounters with specified outcome for that predictor used in the Regression Analysis: Lower/Higher dosage (Number of Patients/analysis cell) | Higher Opioid Dosage (>120 MEQs/day) Ordered† | |||
|---|---|---|---|---|---|---|
| Variable | Odds ratio | 95% Confidence Interval | Odds ratio | 95% Confidence Interval | ||
| Demographics | ||||||
| Age Group: >=65 vs 45–64 | >=65: 354/831 (577) 45–64: 493/1723 (892) |
0.74* | (0.58,0.95)# | >=65: 430/401 (380) 45–64: 690/1033 (634) |
0.56** | (0.40,0.79) |
| Sex: Male vs Female | Male: 353/1427 (765) Female: 667/1602 (997) |
1.66*** | (1.34,2.04) | Male: 510/917 (565) Female: 799/803 (647) |
2.04*** | (1.51,2.75) |
| Patient-Reported Outcomes | ||||||
| Worst Pain Location: Abdomen vs Back | Abdomen: 155/447 (363) Back: 171/670 (464) |
0.59*** | (0.43,0.81) | Abdomen: 185/262 (265) Back: 279/391 (350) |
0.89 | (0.59,1.34) |
| Worst Pain Location: Face/Head/Neck vs Back | Face/Head/Neck: 97/245 (183) Back: 171/670 (464) |
0.65* | (0.43,0.97) | Face/Head/Neck: 107/138 (133) Back: 279/391 (350) |
1.0 | (0.60,1.67) |
| Worst Pain Location: Hip vs Back | Hip: 62/152 (136) Back: 171/670 (464) |
0.64* | (0.42,0.97) | Hip: 81/71 (91) Back: 279/391 (350) |
0.6 | (0.34,1.06) |
| Average Pain 24 HRS | 4049 (1389) | 1.02 | (0.97,1.08) | 3029 (1082) | 1.04 | (0.96,1.12) |
| Percent Pain Relief | 4049 (1389) | 1.02*** | (1.01,1.02) | 3029 (1082) | 1.01*** | (1.01,1.02) |
| Pain Interference | 4049 (1389) | 1.0 | (0.95,1.05) | 3029 (1082) | 0.97 | (0.91,1.03) |
| CMSAS Physical subscale | 4049 (1389) | 1.18* | (1.01,1.38) | 3029 (1082) | 1.29** | (1.06,1.56) |
| CMSAS Psychological subscale | 4049 (1389) | 0.84*** | (0.77,0.92) | 3029 (1082) | 0.97 | (0.87,1.09) |
| EQ-5D Index | 4049 (1389) | 0.54* | (0.32,0.93) | 3029 (1082) | 0.27*** | (0.14,0.52) |
| Clinical Diagnosis | ||||||
| Anxiety | 486/1557 (872) | 1.11 | (0.87,1.42) | 650/907 (626) | 0.84 | (0.61,1.17) |
| Depression | 478/1419 (764) | 1.03 | (0.81,1.32) | 548/871 (529) | 1.55** | (1.11,2.17) |
| Substance Abuse | 17/68 (60) | 1.12 | (0.64,1.98) | 27/41 (48) | 0.70 | (0.34,1.42) |
| Tobacco Use Disorder | 22/45 (56) | 0.50** | (0.29,0.84) | 19/26 (35) | 0.67 | (0.29,1.54) |
*
0.01<p<0.05;
**
0.001<p<=0.01;
***
p<=0.001;
†
Odds ratio and confidence intervals from general estimating equation models.