Table 3.
Abnormal cell counts at day 3 after stroke and their ability to predict infection and good outcome. Data are displayed as the odds ratio (OR) and 95% confidence interval (CI).
| Infection by Day 15* | uncontrolled | controlled for NIHSS | controlled for NIHSS and age | controlled for NIHSS, age and cortisol | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |||
| WBCs | 5.46 | 0.001 | 1.89 | NS | 1.98 | NS | 1.92 | NS | ||
| (>10,000/μL) | (1.96, 15.20) | (0.52, 6.89) | (0.52, 7.52) | (0.45, 8.24) | ||||||
| PMNs | 3.92 | 0.01 | 0.94 | NS | 0.94 | NS | 0.65 | NS | ||
| (>7,000/μL) | (1.34, 11.44) | (0.23, 3.88) | (0.21, 4.27) | (0.12, 3.54) | ||||||
| lymphocytes | 2.99 | 0.09 | 1.42 | NS | 1.02 | NS | 0.58 | NS | ||
| (<1,000/μL) | (0.85, 10.51) | (0.24, 6.42) | (0.16, 6.43) | (0.07, 5.01) | ||||||
| monocytes | 8.52 | <0.001 | 2.57 | NS | 2.78 | NS | 2.08 | NS | ||
| (>800/μL) | (2.78, 26.15) | (0.65, 10.11) | (0.65, 11.94) | (0.43, 10.15) | ||||||
| eosinophils | 4.66 | 0.008 | 0.76 | NS | 0.97 | NS | 0.53 | NS | ||
| (<50/μL) | (1.51, 14.39) | (0.16, 1.29) | (0.17, 5.67) | (0.07, 3.88) | ||||||
| Bad Outcome (mRS>3) at 90 days | uncontrolled | controlled for NIHSS | controlled for NIHSS and age | controlled for NIHSS, age and cortisol | controlled for NIHSS, age cortisol and infection | |||||
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| WBCs | 5.73 | 0.002 | 1.39 | NS | 1.74 | NS | 1.43 | NS | 0.73 | NS |
| (>10,000/μL) | (1.93, 16.96) | (0.31, 6.12) | (0.34, 8.73) | (0.25, 8.26) | (0.10, 5.66) | |||||
| PMNs | 5.83 | 0.003 | 1.27 | NS | 1.41 | NS | 1.22 | NS | 0.99 | NS |
| (>7,000/μL) | (1.84, 18.42) | (0.27, 5.92) | (0.29, 7.00) | (0.22, 6.72) | (0.14, 6.89) | |||||
| lymphocytes | 11.20 | <0.001 | 15.57 | 0.01 | 17.21 | 0.009 | 17.74 | 0.01 | 22.86 | 0.01 |
| (<1,000/μL) | (3.00, 41.83) | (1.94, 124.68) | (2.06, 144.00) | (1.79, 138.81) | (1.95, 267.65) | |||||
| monocytes | 9.97 | <0.001 | 1.22 | NS | 1.15 | NS | 0.78 | NS | 0.44 | NS |
| (>800/μL) | (2.98, 33.31) | (0.23, 6.55) | (0.20, 6.44) | (0.12, 5.19) | (0.05, 4.13) | |||||
| eosinophils | 5.10 | 0.008 | 0.64 | NS | 0.71 | NS | 0.49 | NS | 0.51 | NS |
| (<50/μL) | (1.52, 17.12) | (0.11, 3.68) | (0.12, 4.40) | (0.07, 3.32) | (0.06, 4.30) | |||||
NIHSS=National Institutes of Health Stroke Scale score, WBCs=white blood cells, PMNs=polymorphonuclear cells, NS=not significant (P>0.10).
*
patients with infection up to day 3 are excluded