Skip to main content
. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Genet Epidemiol. 2017 Nov 26;42(2):146–155. doi: 10.1002/gepi.22093

Figure 1.

Figure 1

Quantile-quantile plots for the interaction-only, joint tests and tests for main effect of G in the analysis of National Cancer Institute Lung Cancer GWAS. Tests for associations are performed between risk of lung cancer and each of approximately 5.3 million common SNPs accounting for interactions with smoking status (never, former, and current) of the individuals. Each curve pertains to SNPs such that MAF > 0.05, the imputation quality reported to have info measure IA ≥ 0.5, and the p-values from all the seven tests are available. GWAS, genome-wide association studies; SNP, single nucleotide polymorphism; MAF, minor allele frequency; PT, prospective; RT, restrospective; EB, empirical Bayes.