Table 1.
Lines of rhodopsin transgenic (Tg) rats, terminology, and ratio of the amount of mutant opsin to wild-type, endogenous opsin in the retinas of Tg rats
| Line | Abbreviation | RRRC*# | Rate of Degeneration | RT-PCR Ratio of Tg to Endogenous Opsin mRNA | Westerns Ratio of Tg to Endogenous Opsin |
|---|---|---|---|---|---|
| SD-Tg(P23H)1Lav | P23H-1** | 639 | Moderate | 0.1:1 | NA |
| SD-Tg(P23H)3Lav | P23H-3 | 641 | Slow | <0.05:1 | NA |
| SD-Tg(P23H)2Lav | P23H-2 | 640 | Very Slow | Trace | NA |
|
| |||||
| SD-Tg(S334ter)7Lav | S334ter-7** | 642 | Extremely Fast | 5:1 | 1.4:1 |
| SD-Tg(S334ter)3Lav | S334ter-3 | 643 | Very Fast | 1.5:1 | — |
| SD-Tg(S334ter)5Lav | S334ter-5 | 644 | Fast | 0.4:1 | 1:1 |
| SD-Tg(S334ter)4Lav | S334ter-4 | 645 | Moderate | 0.1:1 | 0.7:1 |
| SD-Tg(S334ter)9Lav | S334ter-9 | 646 | Very Slow | <0.05:1 | 0.05:1 |
*
Rat Resource & Research Center Strain #, Columbia, Missouri
**
or P23H Line 1, S334ter Line 7, etc.