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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Genet Epidemiol. 2017 Dec 10;42(2):134–145. doi: 10.1002/gepi.22105

Table 3.

Simulation 3: Comparison of empirical powers (based on corrected critical values) for two studies with overlapping samples at level α = 10−4. Power is estimated based on 104 non-null datasets. For a given association scenario, the method with highest power is bold-faced and the method with lowest power is italicized.

Study type No. of traits associated Meta-analysis method

SHom SHet minP aSPU metaMANOVA metaUSAT
1 0.984 0.852 0.034 0.018 1.000 1.000
Homogeneous 2 0.000 0.048 0.051 0.099 0.083 0.093
3 0.244 0.127 0.077 0.300 0.146 0.216
4 0.005 0.485 0.103 0.435 0.456 0.472

1 0.101 0.495 0.006 0.001 0.865 0.807
Heterogeneous 2 0.000 0.004 0.009 0.006 0.007 0.006
3 0.007 0.009 0.011 0.012 0.012 0.012
4 0.001 0.038 0.018 0.026 0.041 0.034