Table 3.
Effect of Spirulina fusiformis on GST, Gpx, GSH against STZ-induced rats
| Parameters | Glutathione-S-transferase (nmol of CDNB–GSH conjugate formed/min/mg protein) | Glutathione peroxidase (μg of GSH utilized/min/mg protein) | Reduced glutathione (nmol/mg protein) | |||
|---|---|---|---|---|---|---|
| Liver | Kidney | Liver | Kidney | Liver | Kidney | |
| Group I | 93.80 ± 0.31 | 88.78 ± 0.21 | 67.10 ± 0.59 | 70.41 ± 0.65 | 51.53 ± 0.59 | 48.76 ± 0.67 |
| Group II | 47.79 ± 0.04a* | 50.13 ± 0.94a* | 29.08 ± 0.14a* | 33.65 ± 0.72a* | 25.22 ± 0.20a* | 26.40 ± 0.53a* |
| Group III | 86.67 ± 0.09a*b* | 87.09 ± 0.01b* | 65.90 ± 0.65a*b* | 69.19 ± 0.91b* | 53.43 ± 0.10b* | 42.08 ± 0.76b* |
| Group IV | 92.21 ± 0.24a*b*c* | 85.81 ± 0.43a*b* | 61.45 ± 0.23b*c* | 64.05 ± 0.76b* | 48.51 ± 0.46b*c* | 45.89 ± 0.10a*c* |
| Group V | 90.23 ± 0.11b*d* | 90.02 ± 0.71a*d* | 66.82 ± 0.70a*b*c*d* | 71.32 ± 0.18b*c*d* | 54.83 ± 0.32a*c*d* | 40.45 ± 0.05b*d* |
Each value represents the mean ± SD of six rats. Comparisons were made as follows: a-group I vs groups II, III, IV, V; b-group II vs group III, IV,V; c-group III vs group IV, V; d-group IV vs group V. The symbols represent statistical significance at *P < 0. 05. Statistical analysis was calculated by one-way ANOVA followed by the Student Newman–Keul’s test