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. 2018 Feb 13;8:2900. doi: 10.1038/s41598-018-20998-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Schematic diagrams of fabrication, and (B) usage of the device. Channels are fabricated by depositing a base PDMS layer (A1). After solidification, a capillary tube is placed on top of the base layer (A2). A second PDMS layer is then deposited (A3). The capillary tube is removed (A4), leaving an open channel. The device is operated by introducing a liquid solution to fill one half of the channel (B1). A second solution is introduced from the opposite end (B2). Upon coalescence of the two menisci, the solutions react at the liquid interface, forming a membrane via self-assembly of the suspended molecules (B3).