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Changes to adipose tissue and adipocytes with age and obesity compared to young and lean, respectively.
| Broader Tissue-Specific Changes |
||||
|---|---|---|---|---|
| Ageing | Ageing references | Obesity | Obesity references | |
| Adipocyte size | ↑ | (216) | ↑ | (31) |
| Endoplasmic reticulum stress | ↑ | (176, 177) | ↑ | (82, 85) |
| Mitochondrial dysfunction | ↑ | (181) | ↑ | (217) |
| Stem cell exhaustion | ↑ | (13) | ↑ | (13) |
| Tissue blood flow | ↓ | (180) | ↓ | (36, 178) |
| Tissue hypoxia | ↑ | ↑ | ||
↓, decrease; ↑, increase.
