Table 6.
Changes in the expression of proteins within adipose tissue (adipocytes and cells of the stromal fraction) with age and obesity compared to young and lean, respectively.
| Proteins expressed within adipose tissue |
||||
|---|---|---|---|---|
| Ageing | Ageing references | Obesity | Obesity references | |
| CCR-2 | ↑ | (170) | ↑ | (223) |
| CCR-5 | ↑ | (170) | ↑ | (111, 112) |
| CCR-7 | ↓ | (170) | ↓ | (224) |
| CX3CR-1 | ↓ | (170) | ↑ ← → | (225–228) |
| CXCR-3 | ↑ | (170) | ↑ | (229) |
| PGE2 | ↑ | (51) | ↑ | (230) |
| PPAR-γ | ↓ | (51) | ↑ | (231) |
↓, decrease; ↑, increase; ← →, little or no change or equivocal data; CCR, (C-C motif) chemokine receptor; CX3CR-1, (C-X3-C motif) chemokine receptor 1; CXCR-3, (C-X-C motif) chemokine receptor 3; PGE2, prostaglandin E2; PPAR-γ, peroxisome proliferator-activated receptor gamma.