Table 2.

Amyloid-related image abnormalities with vasogenic oedema and/or sulcal effusion (ARIA-E) rating scale

FLAIR finding	Baseline scoring	ARIA-E after treatment initiation	Evolution of ARIA-E
Parenchymal hyperintensity	ARWMC score by 1. Lesion size 2. Region and side (if yes – ARIA-E like?)	Count new focal lesions 1. By region and side 2. By largest cross-sectional diameter Score 0- 0 Score 1- Monofocal ≤ 2 cm Score 2- Multifocal ≤ 2 cm Score 3- Any lesion > 2 but < 4 cm Score 4- Any lesion >4 cm Score 5- Entire lobe	Increase ARIA-E ARIA-E unchanged Partial resolution Full resolution N/A initial identification N/A other pathology
Sulcal hyperintensity	Yes / No	Count new focal lesions 1. By region and side 2. By largest cross-sectional diameter Score 0- 0 Score 1- Monofocal ≤ 2 cm Score 2- Multifocal ≤ 2 cm Score 3- Any lesion > 2 but < 4 cm Score 4- Any lesion >4 cm Score 5- Entire lobe	Increase ARIA-E ARIA-E unchanged Partial resolution Full resolution N/A initial identification N/A other pathology
Swelling	Yes / No	Count new focal lesions 1. By region and side 2. By largest cross-sectional diameter Score 0-0 Score 1- Monofocal ≤ 2 cm Score 2- Multifocal ≤ 2 cm Score 3- Any lesion > 2 but < 4 cm Score 4- Any lesion >4 cm Score 5- Entire lobe	Increase ARIA-E ARIA-E unchanged Partial resolution Full resolution N/A initial identification N/A other pathology