miR-151-3p downregulates Stat3 dependent genes in macrophages. Macrophages were stimulated with or without 100 ng/ml LPS for the indicated time points. The expression of IL-6 (a), IL-1b (b), Ccl5 (c), Ccl12 (d), Socs3 (e) and Tnf-α (f) was measured using RT-qPCR. Data are shown as the mean±s.d. (n=3) of one representative experiment. Similar results were obtained in at least three independent experiments. *P<0.05; **P<0.01, unpaired Student's t-test.