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. 2017 Sep 8;32(2):262–286. doi: 10.1038/eye.2017.181

Table 1. Comparison of OCTA versus conventional angiography such as fundus FA and ICGA.

OCTA FFA ICGA
New technology not validated Well-validated technology Well-validated technology
Correlation to multimodal imaging and histology Correlation to multimodal imaging and histology  
Non-invasive, no need for dye Invasive, need for dye risk of anaphylaxis Invasive, need for dye risk of anaphylaxis  
Rapid acquisition time Time-consuming to perform Time-consuming to perform  
Interpretation may require more time Image viewing may be faster Image viewing may be faster  
Provides depth information of both retinal and choroidal vasculature No information about individual layers No information about individual layers  
Able to segment various layers Retina imaged in entirety Choroid imaged in entirety  
Able to image through blood Blockage from blood Able to penetrate blood  
Artefacts may hamper interpretation Less artefact Less artefact  
Detection of flow but not leakage Detection of leakage and activity Detection of leakage and activity  
High resolution down to capillaries in the retina Lower resolution, able to image large retinal vessels but not capillaries Able to image large choroidal vessels but not choriocapillaries  
Small field of view Wide-field option available Wide-field option available  
No stereoscopic function Stereoscopic option Stereoscopic option  
No dynamic video function Video function available Video function available