Table 1.
Effect of acetylsalicylic acid (ASA) and melatonin on sperm parameters in adult mice
| Groups | Motility (%) | Number (×106/ml) | Abnormal head morphology (%) | Abnormal tail morphology (%) | Sperm chromatin integrity (%) | SDF (%) |
|---|---|---|---|---|---|---|
| Control | 63.6 ±5.6 b | 29.7 ± 3.4 b | 4.9±1.7 b | 5.5 ±0.6 b | 82.18±6.17 b | 18.2±2.4 |
| ASA | 51.50 ± 40 adc | 12.6±3.1 acd | 9.21 ± 1.1acd | 14.0 ±1.4 acd | 65.18±3.08 acd | 35.4±4.15 acd |
| Melatonin | 67.4 ± 5.2 b | 32.2 ±3.6 b | 5.2±1.3 b | 5.1 ±0.8 b | 84.18±6.1 b | 16.8±3.3 b |
| ASA+ Melatonin | 60.1 ±3.0 b | 26.8±2.6 b | 6.65±.3 | 7.4±0.3 ab | 78.46±7.2 b | 23.6±3.6 b |
Data are shown as mean±SD. SDF: Sperm DNA fragmentation. a: P<0.001, compared with the control group within the same column; b: P<0.01, compared with the ASA treated group within the same column; c: P<0.01, compared with the melatonin-treated group within the same column; d: P<0.05, compared with the ASA+ melatonin-treated group within the same column